Let It Go and Open Up, an Ensemble of Ion Channel Active States
نویسنده
چکیده
Ligand binding usually moves the target protein from an ensemble of inactive states to a well-defined active conformation. Matthies et al. flip this scheme around, finding that, for the magnesium channel CorA, loss of ligand binding induces an ensemble of conformations that turn the channel on.
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عنوان ژورنال:
- Cell
دوره 164 شماره
صفحات -
تاریخ انتشار 2016